Evidence for Interleaflet Slip During Spreading of Single Lipid Bilayers at Hydrophilic Solids

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Babak Sanii, Kathy Nguyen, Joachim A. Rädler, Atul N. Parikh ChemPhysChem 10, 2787-2790 2009

Slip—the relative mobility of the two leaflets in lipid bilayers—represents a generic mechanical-dynamical process. To establish the presence of interleaflet slip in the surface-spreading lipid membranes, the advancing lipid bilayers are exposed to an intense laser spot, which rapidly bleaches the illuminated fluorophores in a radially symmetric shape (see figure).

DOI:10.1002/cphc.200900372

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